For analysis of QoL,some questionnaires were prepared exclusivelyfor patients suffering from Parkinson’s disease (PD). The two well-knownscales are Parkinson’s Disease Questionnaire (PDQ-39) and Parkinson` s DiseaseQuality of Life Questionnaire (PDQL). Martinez-Martin reported that the qualityof life scales are useful in evaluating the results of rehabilitation and drugtreatment of Parkinson’s disease or neurosurgery 7.Hence, Parkinson’s Disease Questionnaire- 39 is being used in this study. Therefore, analysis ofthe severity of any disease should include not only the clinical factors butalso the psychological & social factors concern the patient. Parkinson’sDisease has a profound negative impact on the Quality of Life (QoL) as pointedout by numerous studies, patients suffer from weakness, dementia, emotionalproblems, sleep disorders, difficulty in speech and balance, depression,diminished cognitive functions and several other lifestyle changes 6.
Quality of Life (QoL) isa multi-dimensional construct, which consists of at least three main domains:physical, mental and social. In medicinal sciences, health-related quality oflife concept is often used by researchers and scientists. It focuses on theimpact of the disease and treatment as well as on patients’ perception of theirlifestyle and on subjective well-being or satisfaction with life 5. Patients are usually prescribedLevodopa, COMT Inhibitors, Dopamine Agonists, Non-Dopaminergic Therapy, etc3. Therefore, assessing of prescriptions associated to the disease is necessaryto improve the therapeutic efficacy and to reduce the side effects & toprovide feedback to the prescribers.
The main aim of this drug utilizationstudy is to facilitate rational drug usage and knowing the efficacy of each oneof them 4. The rampancy of thedisease ranges from 41 people per 100,000 in the fourth decade of life to morethan 1,900 people per 100,000 among those 80 and older 2. Parkinson’s disease (PD)belongs to a group of neurodegenerative conditions called motor system diseases,which are the result of the loss of dopaminergic brain cells. The primarysymptoms of PD are postural instability, or impaired balance and coordination, tremor,or trembling in limbs, jaw, and face rigidity, or stiffness of the limbs andslowness of trunk movement, 1.